Rheumatoid arthritis

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  • Direct renal injury is rare
  • AA Amyloidosis (10-20%, esp. if duration>10 yrs, severe RA, RA factor +)
    • Nephrotic syndrome and renal failure (3-10%)
  • Drug-induced
    • Gold & penicillamine
      • Nephrotic syndrome (membranous nephropathy)
    • NSAID
      • Minimal change disease
      • Acute interstitial nephritis