Stage 2: Silent

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在2018年3月13日 (二) 17:31由Guhjy (對話 | 貢獻)所做的修訂版本
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2-3rd year 40% progress to stage 3 Pathology

  • Thick GBM
    • Heparan sulfate lost
      • Loss of charge selectivity for proteins
        • Proteinuria or albuminuria
  • Mesangial expansion or sclerosis
    • Pathogenesis
  • Glomerular hypertension
  • Proteinuria
  • Advanced glycosylation end products ↑
  • Growth hormone ↑
  • IGF-I ↑
  • Angiotensin II ↑
  • Connective tissues growth factor ↑
  • Transforming growth factor-β
  • Hyperlipidemia