Henoch-Schönlein purpura

在2018年3月14日 (三) 09:48由Guhjy (對話 | 貢獻)所做的修訂版本

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Clinical features
- Young (<20 y/o), palpable purpura, abdominal pain, GI bleeding, arthropathy, fever, fatigue, ~IgA ↑ (50% p’ts), hematuria, proteinuria, macroscopic hematuria immediately after URI in children, NS (uncommon)
- GN is very similar to ~IgA nephropathy
- Skin: Leukocytoclastic vasculitis, dermal ~IgA deposits
Kidney biopsy is indicated only for p’ts with marked proteinuria or renal failure
Treatment
- Similar to ~IgAN
- Corticosteroids or cytotoxics for RPGN
Prognosis
- Good (esp. in children), chronic renal failure & hypertension (rare)
References of Henoch-Schönlein purpura