Stage 2: Silent

出自KMU Wiki

在2018年3月13日 (二) 17:30由Guhjy (對話 | 貢獻)所做的修訂版本
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2-3rd year 40% progress to stage 3 Pathology

  • Thick GBM
    • Heparan sulfate lost
      • Loss of charge selectivity for proteins
        • Proteinuria or albuminuria
  • Mesangial expansion or sclerosis
    • Pathogenesis
  1. Glomerular hypertension
  2. Proteinuria
    1. Advanced glycosylation end products ↑
    2. Growth hormone ↑
    3. IGF-I ↑
    4. Angiotensin II ↑
    5. Connective tissues growth factor ↑
    6. Transforming growth factor-β
    7. Hyperlipidemia
取自"http://wiki.kmu.edu.tw/index.php/Stage_2:_Silent"