Light chain deposition disease
出自KMU Wiki
(修訂版本間差異)
| 在2018年3月14日 (三) 09:52所做的修訂版本 (編輯) Guhjy (對話 | 貢獻) (新頁面: *Light chain-producing monoclonal gammapathies (Paraproteinemia) *Nephrotic syndrome *Hematuria *Renal failure *ESRD *Pathology **κ light chains deposit in the glomerular capill...) ←上一個 |
當前修訂版本 (2018年3月14日 (三) 09:52) (編輯) (撤銷) Guhjy (對話 | 貢獻) (新頁面: *Light chain-producing monoclonal gammapathies (Paraproteinemia) *Nephrotic syndrome *Hematuria *Renal failure *ESRD *Pathology **κ light chains deposit in the glomerular capill...) |
當前修訂版本
- Light chain-producing monoclonal gammapathies (Paraproteinemia)
- Nephrotic syndrome
- Hematuria
- Renal failure
- ESRD
- Pathology
- κ light chains deposit in the glomerular capillary and mesangium (to produce nephrotic syndrome), tubular basement membrane, and Bowman's capsule
- Not fibrillar and do not stain with Congo red, detected with anti-light–chain antibody using immunofluorescence, or as granular deposits along the glomerular capillary (causing nephrotic syndrome) and mesangium, tubular basement membrane, and Bowman's capsule
- Nodular glomerulosclerosis (33%)
- Tubular abnormalities
- κ light chains deposit in the glomerular capillary and mesangium (to produce nephrotic syndrome), tubular basement membrane, and Bowman's capsule
- Poor prognosis esp. if Multiple myeloma
- Treatment (for underlying dis.)
