Stage 4: Overt proteinuria
出自KMU Wiki
- 10-15th year
- Dipstick (+) proteinuria
- Proteinuria >500 mg/day
- Macroalbuminuria (urinary albumin excretion>300 mg/day)
- Nephrotic syndrome
- Hyperkalemia
- type IV RTA
- Hypertension
- A consequence of DN and a risk factor for the progression of DN
- Progressive GFR ↓
- 50% become ESRD within 5-10 yrs
- "Normally sized” kidneys even in chronic renal failure
- Diabetic retinopathy
- 90% in type 1 DM
- 60% in type 2 DM
- Bland urinary sediment