Stage 5: ESRD

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(新頁面: *15-30th year *Brittle diabetes **''Large swings in plasma glucose level'' **More often low plasma glucose level or hypoglycemia due to ***Insulin degradation ↓ ***Renal gluconeogene...)
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  • 15-30th year
  • Brittle diabetes
    • Large swings in plasma glucose level
    • More often low plasma glucose level or hypoglycemia due to
      • Insulin degradation ↓
      • Renal gluconeogenesis ↓
    • Thus, diabetic patients with decreasing plasma glucose levels may sometimes suggest declining renal function
    • Less often high due to insulin resistance ↑
  • Both DM and end-stage renal disease are systemic dis.
    • Microangiopathy, retinopathy, neuropathy, macroangiopathy (cardiovascular disease, atherosclerosis, coronary heart disease), hyperlipidemia, foot ulcer
    • Dialysis is indicated at an earlier stage (serum creatinine ≥ 5~6 mg/dl) than the other uremic p'ts
    • Morbidity and mortality are higher than other ESRD p’ts
    • Renal transplantation