Introduction of diabetic nephropathy

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在2018年3月13日 (二) 17:20所做的修訂版本 (編輯)
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**DCCT (Diabetes Control and Complications Trial) **DCCT (Diabetes Control and Complications Trial)
***Type 1 DM ***Type 1 DM
-***[[http://content.nejm.org/cgi/content/short/329/14/977|NEJM 1993;329:977: The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus]]+***[http://content.nejm.org/cgi/content/short/329/14/977| NEJM 1993;329:977. The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus]
**UKPDS (UK Prospective Diabetes Study) **UKPDS (UK Prospective Diabetes Study)
-*** [[http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T1B-3TX4KPJ-3&_user=2411013&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000051939&_version=1&_urlVersion=0&_userid=2411013&md5=6ce6fc1e30dcd65072e0b0bc72934dff|Lancet 1998;352:837: Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)|]]+*** [http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T1B-3TX4KPJ-3&_user=2411013&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000051939&_version=1&_urlVersion=0&_userid=2411013&md5=6ce6fc1e30dcd65072e0b0bc72934dff| Lancet 1998;352:837. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)]
***Type 2 DM ***Type 2 DM
-**Effects on macroangiopathy (cardiovascular disease and atherosclerosis) are less certain+**Intensive glycemic control (HbA1C 6.5~7%) prevents microangiopathy in newly diagnosed DM, but effects on macroangiopathy (cardiovascular diseases and atherosclerosis) are less certain

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