Introduction of diabetic nephropathy

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	**DCCT (Diabetes Control and Complications Trial)		**DCCT (Diabetes Control and Complications Trial)
	***Type 1 DM		***Type 1 DM
-	***NEJM 1993;329:977: [The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus|http://content.nejm.org/cgi/content/short/329/14/977]	+	***NEJM 1993;329:977: [[The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus|http://content.nejm.org/cgi/content/short/329/14/977]]
	**UKPDS (UK Prospective Diabetes Study)		**UKPDS (UK Prospective Diabetes Study)
	***Type 2 DM		***Type 2 DM
	**Effects on macroangiopathy (cardiovascular disease and atherosclerosis) are less certain		**Effects on macroangiopathy (cardiovascular disease and atherosclerosis) are less certain

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在2018年3月13日 (二) 17:15所做的修訂版本

• The most common cause of incident ESRD and the 2nd commonest cause of prevalent ESRD in Taiwan
• Prevalence
  • 40% in type 1 and 2 DM
  • Because type 2 DM is much more common than type 1 DM, most diabetic nephropathy patients have type 2 DM
• Importance of hyperglycemia in DN
  • DCCT (Diabetes Control and Complications Trial)
    • Type 1 DM
    • NEJM 1993;329:977: http://content.nejm.org/cgi/content/short/329/14/977
  • UKPDS (UK Prospective Diabetes Study)
    • Type 2 DM
  • Effects on macroangiopathy (cardiovascular disease and atherosclerosis) are less certain