Cryoglobulinemia

出自KMU Wiki

(修訂版本間差異)
跳轉到: 導航, 搜索
在2018年3月14日 (三) 09:48所做的修訂版本 (編輯)
Guhjy (對話 | 貢獻)
(新頁面: *Cryoglobulins are cold-precipitable monoclonal or polyclonal immunoglobulins *May be associated with vasculitis **Palpable purpura, arthralgias, weakness, neuropathy, MPGN, RPGN (rar...)
←上一個
當前修訂版本 (2018年3月14日 (三) 09:48) (編輯) (撤銷)
Guhjy (對話 | 貢獻)
(新頁面: *Cryoglobulins are cold-precipitable monoclonal or polyclonal immunoglobulins *May be associated with vasculitis **Palpable purpura, arthralgias, weakness, neuropathy, MPGN, RPGN (rar...)
 

當前修訂版本

  • Cryoglobulins are cold-precipitable monoclonal or polyclonal immunoglobulins
  • May be associated with vasculitis
    • Palpable purpura, arthralgias, weakness, neuropathy, MPGN, RPGN (rare)
    • Rheumatoid factor (may be a surrogate for cryoglobulin), complement ↓, ESR ↑, anemia
    • Idiopathic
      • Also called "essential mixed cryoglobulinemia"
      • Mostly due to HCV infection
      • 5% of ~HCV-infected p'ts have "essential mixed cryoglobulinemia"
      • MPGN
        • ESRD (15%)
          • 40% later experiencing fatal cardiovascular disease, infection, or liver failure
      • Treatment for HCV (α-interferon)
    • Secondary
      • Multiple myeloma, lymphoproliferative disorders, connective tissue diseases, infection, liver disease