Introduction of diabetic nephropathy
出自KMU Wiki
(修訂版本間差異)
| 在2018年3月13日 (二) 17:20所做的修訂版本 (編輯) Guhjy (對話 | 貢獻) ←上一個 |
當前修訂版本 (2018年3月27日 (二) 12:43) (編輯) (撤銷) Guhjy (對話 | 貢獻) |
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| (7個中途的修訂版本沒有顯示。) | |||
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| **DCCT (Diabetes Control and Complications Trial) | **DCCT (Diabetes Control and Complications Trial) | ||
| ***Type 1 DM | ***Type 1 DM | ||
| - | *** | + | ***[http://content.nejm.org/cgi/content/short/329/14/977| NEJM 1993;329:977. The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus] |
| **UKPDS (UK Prospective Diabetes Study) | **UKPDS (UK Prospective Diabetes Study) | ||
| - | *** | + | *** [http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T1B-3TX4KPJ-3&_user=2411013&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000051939&_version=1&_urlVersion=0&_userid=2411013&md5=6ce6fc1e30dcd65072e0b0bc72934dff| Lancet 1998;352:837. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)] |
| ***Type 2 DM | ***Type 2 DM | ||
| - | ** | + | **Intensive glycemic control (HbA1C 6.5~7%) prevents microangiopathy in newly diagnosed DM, but effects on macroangiopathy (cardiovascular diseases and atherosclerosis) are less certain |
當前修訂版本
- The most common cause of incident ESRD and the 2nd commonest cause of prevalent ESRD in Taiwan
- Prevalence
- 40% in type 1 and 2 DM
- Because type 2 DM is much more common than type 1 DM, most diabetic nephropathy patients have type 2 DM
- Importance of hyperglycemia in DN
- DCCT (Diabetes Control and Complications Trial)
- UKPDS (UK Prospective Diabetes Study)
- Intensive glycemic control (HbA1C 6.5~7%) prevents microangiopathy in newly diagnosed DM, but effects on macroangiopathy (cardiovascular diseases and atherosclerosis) are less certain
